Paget disease of the vulva
نویسندگان
چکیده
منابع مشابه
Paget Disease of the Vulva: Diagnosis by Immunohistochemistry
The objective of this paper is to report a case of extramammary Paget disease of the vulva, to describe its diagnosis, surgical treatment, and outcome, and to discuss the general characteristics of this pathology. This is a rare neoplasm, found principally in areas in which apocrine and eccrine glands are numerous. This case report is relevant to the literature since the differential diagnosis ...
متن کاملExtramammary Paget Disease of the Vulva - Case Report.
Extramammary Paget disease (EPD) is a rare malign neoplasm that may affect the vulva and has manifestations common to benign diseases such as itching, pain and eczema. This leads to delay in diagnosis and consequent worse prognosis. The definitive diagnosis is obtained by biopsy of the vulva, which shows Paget cells. The treatment of choice is wide excision with margins, which leads to sequelae...
متن کاملExtension of extramammary Paget disease of the vulva to the cervix.
Extramammary Paget disease of the vulva was found in association with vulval adenocarcinoma in an elderly woman who also had a uterine prolapse. The characteristic histological appearances of extramammary Paget disease were masked by striking reactive changes in the squamous epithelium. Primary excision of both the intraepithelial and invasive disease appeared complete. However, a subsequent hy...
متن کاملExtramammary Paget disease of the vulva: immunohistochemical analysis of neoangiogenesis and epithelial-mesenchymal transition markers expression.
BACKGROUND Extra-mammary Paget's disease of the vulva (EMPDV) is an infrequent chronic disease that often recurs. The aim of the study was to assess the presence of neoangiogenesis and the expression of epithelial-mesenchymal transition (EMT) markers in EMPDV, and their potential correlation with stromal invasion. METHODS All the women consecutively treated for EMPDV at our Institute, between...
متن کامل[paget's Disease of the Vulva].
OBJECTIVE Our goal was to review our experience with Paget's disease of the vulva relative to initial examination, treatment, and oncologic outcome. STUDY DESIGN Patients who were treated for extramammary Paget's disease of the vulva at the University of South Florida were identified in our vulvar cancer database for the period 1988 through 2000. The charts were reviewed, and the data were co...
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ژورنال
عنوان ژورنال: Critical Reviews in Oncology/Hematology
سال: 2016
ISSN: 1040-8428
DOI: 10.1016/j.critrevonc.2016.03.008